Thrombin receptor mediated signals induce expressions of interleukin 6 and granulocyte colony stimulating factor via NF-κB activation in synovial fibroblasts

OBJECTIVE—To clarify the mechanism of thrombin receptor mediated signal transduction and the induction of cytokines by thrombin stimulation in rheumatoid synovial fibroblasts.
METHODS—Cytokines were measured by enzyme linked immunosorbent assay (ELISA) in the supernatants of cultured rheumatoid syno...

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Bibliografiska uppgifter
Huvudupphovsmän: Shin, H., Kitajima, I., Nakajima, T., Shao, Q., Tokioka, T., Takasaki, I., Hanyu, N., Kubo, T., Maruyama, I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
Ämnen:
Extended Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752754/
https://ncbi.nlm.nih.gov/pubmed/10343541
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