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TCRβ spectratyping in RA: evidence of clonal expansions in peripheral blood lymphocytes

OBJECTIVE—To compare the TCRβ repertoire of peripheral blood CD8 enriched (CD8+) and depleted (CD8−) T cells in rheumatoid arthritis (RA) patients and controls using CDR3 length analysis (spectratyping).
METHODS—CD8+ and CD8− T cells were separated from 14 RA patients and 12 controls, using magnetic...

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Detalhes bibliográficos
Main Authors: Hall, F, Thomson, K, Procter, J, McMichael, A, Wordsworth, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752604/
https://ncbi.nlm.nih.gov/pubmed/9741318
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