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Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae.

A 19-kDa lipoprotein from Mycobacterium tuberculosis was expressed as a recombinant antigen in the nonpathogenic mycobacterial host strain M. vaccae. Immunization of mice with the recombinant M. vaccae resulted in induction of a strong type 1 immune response to the 19-kDa antigen, characterized by i...

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Detalhes bibliográficos
Main Authors: Abou-Zeid, C, Gares, M P, Inwald, J, Janssen, R, Zhang, Y, Young, D B, Hetzel, C, Lamb, J R, Baldwin, S L, Orme, I M, Yeremeev, V, Nikonenko, B V, Apt, A S
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175231/
https://ncbi.nlm.nih.gov/pubmed/9125572
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