Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae.

A 19-kDa lipoprotein from Mycobacterium tuberculosis was expressed as a recombinant antigen in the nonpathogenic mycobacterial host strain M. vaccae. Immunization of mice with the recombinant M. vaccae resulted in induction of a strong type 1 immune response to the 19-kDa antigen, characterized by i...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Abou-Zeid, C, Gares, M P, Inwald, J, Janssen, R, Zhang, Y, Young, D B, Hetzel, C, Lamb, J R, Baldwin, S L, Orme, I M, Yeremeev, V, Nikonenko, B V, Apt, A S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9125572/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.5.1856-1862.1997
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