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H-89 inhibits transient outward and inward rectifier potassium currents in isolated rat ventricular myocytes
1. Voltage clamp was used to investigate the effects of N-[2-p-bromo-cinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), a potent inhibitor of PKA, on transient outward K(+) current (I(to)) and inward rectifying K(+) current (I(K1)) in rat cardiac muscle. 2. Initial experiments, performed using d...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1752020/ https://ncbi.nlm.nih.gov/pubmed/16799649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706810 |
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