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AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain

1. An attractive alternative to the use of direct agonists at the cannabinoid receptor type 1 (CB1) in the control of neuropathic pain may be to potentiate the actions of endogenous cannabinoids. Thus, the effects of AM404, an inhibitor of anandamide uptake, were assessed in an experimental model of...

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Detalhes bibliográficos
Main Authors: Costa, Barbara, Siniscalco, Dario, Trovato, Anna Elisa, Comelli, Francesca, Sotgiu, Maria Luisa, Colleoni, Mariapia, Maione, Sabatino, Rossi, Francesco, Giagnoni, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751928/
https://ncbi.nlm.nih.gov/pubmed/16770320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706798
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