Inhibition of lipopolysaccharide-induced transcription factor Sp1 binding by spectrally pure diphosphoryl lipid A from Rhodobacter sphaeroides, protein kinase inhibitor H-8, and dexamethasone.

The transcription factor Sp1 plays a crucial role in the monocyte-specific expression of CD14, a binding site (or putative receptor) for lipopolysaccharide (LPS) complexes with LPS-binding protein (LBP). By using RAW 264.7 macrophages treated with spectrally pure deep-rough-chemotype hexa-acyl LPS f...

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Pubblicato in:	Infect Immun
Autori principali:	Jarvis, B W, Qureshi, N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9125541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.5.1640-1643.1997
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