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Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats

1. The overall aim of this study was to determine if adrenomedullin (AM) protects against myocardial ischaemia (MI)-induced arrhythmias via nitric oxide (NO) and peroxynitrite. 2. In sham-operated rats, the effects of in vivo administration of a bolus dose of AM (1 nmol kg(−1)) was assessed on arter...

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Detalhes bibliográficos
Main Authors: Looi, Yee Hoo, Kane, Kathleen A, McPhaden, Allan R, Wainwright, Cherry L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751863/
https://ncbi.nlm.nih.gov/pubmed/16715121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706771
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