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Pharmacological assessment of the duration of action of glycopyrrolate vs tiotropium and ipratropium in guinea-pig and human airways

1. Our study was aimed at investigating the duration of the bronchodilator action of the antimuscarinc drug glycopyrrolate compared to tiotropium and ipratropium. 2. In the guinea-pig isolated trachea, the time (t(1/2)) necessary for a contractile response to carbachol (0.3 μM) to return to 50% reco...

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Dettagli Bibliografici
Autori principali: Villetti, Gino, Bergamaschi, Marco, Bassani, Franco, Bolzoni, Pier Tonino, Harrison, Selena, Gigli, Paolo M, Janni, Alberto, Geppetti, Pierangelo, Civelli, Maurizio, Patacchini, Riccardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751556/
https://ncbi.nlm.nih.gov/pubmed/16565730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706724
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