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Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons

1. Aminoglutethimide is a clinically available drug that suppresses steroid biosynthesis by inhibiting enzymes such as cytochrome P450scc and aromatase. Because several members of neurosteroids regulate glutamate receptors, we investigated the effect of aminoglutethimide on cell death induced by ove...

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Detalhes bibliográficos
Main Authors: Shirakawa, Hisashi, Katsuki, Hiroshi, Kume, Toshiaki, Kaneko, Shuji, Akaike, Akinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751506/
https://ncbi.nlm.nih.gov/pubmed/16474421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706636
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