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Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons
1. Aminoglutethimide is a clinically available drug that suppresses steroid biosynthesis by inhibiting enzymes such as cytochrome P450scc and aromatase. Because several members of neurosteroids regulate glutamate receptors, we investigated the effect of aminoglutethimide on cell death induced by ove...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751506/ https://ncbi.nlm.nih.gov/pubmed/16474421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706636 |
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