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The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D–lysophosphatidic acid receptor axis and 5-HT(1A) receptors in rat brain sections
1. The basic secretagogues, such as compound 48/80 (c48/80) and mastoparans, are widely used histamine-releasing agents and their mechanism of action is commonly attributed to a direct, receptor-bypassing property to activate the G(i/o) class of G proteins. 2. We tested here whether c48/80 could dir...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751339/ https://ncbi.nlm.nih.gov/pubmed/16415902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706671 |
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