BODIPY®-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 and Y5 receptor subtypes

1. N-terminal labelled fluorescent BODIPY®-NPY peptide analogues were tested in Y(1), Y(2), Y(4) and Y(5) receptor-binding assays performed in rat brain membrane preparations and HEK293 cells expressing the rat Y(1), Y(2), Y(4) and Y(5) receptors. 2. BODIPY®TMR/FL-[Leu(31), Pro(34)]NPY/PYY were able...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dumont, Yvan, Gaudreau, Pierrette, Mazzuferi, Manuela, Langlois, Daniel, Chabot, Jean-Guy, Fournier, Alain, Simonato, Michele, Quirion, Rémi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751241/
https://ncbi.nlm.nih.gov/pubmed/16231000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706425
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