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Subtype-specific actions of β-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (α7, α4β2, α3β4) expressed in Xenopus laevis oocytes

1. Two-electrode voltage-clamp electrophysiology has been used to study the actions of two amyloid peptides (Aβ(1–42), Aβ(1–40)) on α7, α4β2 and α3β4 recombinant human neuronal nicotinic acetylcholine receptors (nicotinic AChRs), heterologously expressed in Xenopus laevis oocytes. 2. The application...

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Détails bibliographiques
Auteurs principaux: Pym, Luanda, Kemp, Mark, Raymond-Delpech, Valérie, Buckingham, Steven, Boyd, C A R, Sattelle, David
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751230/
https://ncbi.nlm.nih.gov/pubmed/16184187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706403
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