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Effects of combined inhibition of the Na(+)–H(+) exchanger and angiotensin-converting enzyme in rats with congestive heart failure after myocardial infarction

1. We investigated the single vs the combined long-term inhibition of Na(+)–H(+) exchanger-1 (NHE-1) and ACE in rats with congestive heart failure induced by myocardial infarction (MI). 2. Rats with MI were randomized to receive either placebo, cariporide (3000 p.p.m. via chow), ramipril (1 mg kg(−1...

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Detalhes bibliográficos
Main Authors: Ruetten, Hartmut, Gehring, Doris, Hiss, Katrin, Schindler, Ursula, Gerl, Martin, Busch, Andreas E, Schaefer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751205/
https://ncbi.nlm.nih.gov/pubmed/16151439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706381
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