Selectivity of d[Cha(4)]AVP and SSR149415 at human vasopressin and oxytocin receptors: evidence that SSR149415 is a mixed vasopressin V(1b)/oxytocin receptor antagonist

1. A possible role of arginine vasopressin (AVP) V(1b) receptor subtype in stress-related disorders has been recently highlighted by the discovery of the agonist [1-deamino-4-cyclohexylalanine] AVP (d[Cha(4)]AVP) and the antagonist SSR149415. Both compounds have been proposed to target specifically...

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Autors principals: Griffante, Cristiana, Green, Andrew, Curcuruto, Ornella, Haslam, Carl P, Dickinson, Bryony A, Arban, Roberto
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751202/
https://ncbi.nlm.nih.gov/pubmed/16158071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706383
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