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Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells

1. The effect of the KCNQ channel blockers XE991, chromanol 293B and linopirdine, was studied on voltage-dependent K(+) currents in smooth muscle cells dissociated freshly from mouse portal vein (mPV) and isometric tension recordings from whole mPV. 2. Voltage clamp experiments showed XE991 inhibite...

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Détails bibliographiques
Auteurs principaux: Yeung, Shuk Yin M, Greenwood, Iain A
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751185/
https://ncbi.nlm.nih.gov/pubmed/16056238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706342
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