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TRPV1 activation results in disruption of the blood–brain barrier in the rat

1. We have examined the role of TRPV1 activation in disrupting the blood–brain barrier by measuring the permeability of single pial venular capillaries in anaesthetized rats. 2. Capsaicin application to the brain surface resulted in increased permeability, maximal 2.1±0.12 × 10(−6) cm s(−1) (mean±s....

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Hlavní autoři: Hu, De-En, Easton, Alexander S, Fraser, Paul A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751183/
https://ncbi.nlm.nih.gov/pubmed/16056236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706350
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