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Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676
1. The skeletal muscle Ca(2+) release channel, the ryanodine receptor, is activated by the trypanocidal drug suramin via the calmodulin-binding site. As calmodulin activates and inhibits the ryanodine receptor depending on whether Ca(2+) is absent or present, suramin analogues were screened for inhi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751178/ https://ncbi.nlm.nih.gov/pubmed/16056233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706359 |
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