Interleukin-12 suppresses immunoglobulin E production but enhances immunoglobulin G4 production by human peripheral blood mononuclear cells.

The effect of interleukin-12 (IL-12) on human immunoglobulin G4 (IgG4) and IgE production was examined with cells derived from filarial patients and European controls. IL-12 inhibited IgE release but enhanced IgG4 production in cultures of peripheral blood mononuclear cells stimulated with anti-CD2...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	de Boer, B A, Kruize, Y C, Rotmans, P J, Yazdanbakhsh, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9038328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.3.1122-1125.1997
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