Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking

Nitric oxide (NO) is a highly diffusible and short-lived physiological messenger. Despite its diffusible nature, NO modifies thiol groups of specific cysteine residues in target proteins and alters protein function via S-nitrosylation. Although intracellular S-nitrosylation is a specific posttransla...

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Main Authors: Iwakiri, Yasuko, Satoh, Ayano, Chatterjee, Suvro, Toomre, Derek K., Chalouni, Cecile M., Fulton, David, Groszmann, Roberto J., Shah, Vijay H., Sessa, William C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1750883/
https://ncbi.nlm.nih.gov/pubmed/17170139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605907103
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