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Human T-cell clones to the 70-kilodalton heat shock protein of Mycobacterium leprae define mycobacterium-specific epitopes rather than shared epitopes.

The mycobacterial 70-kDa heat shock protein (Hsp70) is a dominant antigen during the human T-cell response to mycobacterial infection despite the conserved sequence with the human homolog. To determine whether this response is pathogen specific, CD4+ T-cell clones were isolated from Mycobacterium le...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Adams, E, Basten, A, Rodda, S, Britton, W J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9038316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.3.1061-1070.1997
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