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Quantification of the relative contribution of major histocompatibility complex (MHC) and non-MHC genes to human immune responses to foreign antigens.

Understanding the extent to which genetic factors influence the immune response is important in the development of subunit vaccines. Associations with HLA gene polymorphisms appear insufficient to explain the range of variation in immune responses to vaccines and to infections by major pathogens. In...

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Autores principales: Jepson, A, Banya, W, Sisay-Joof, F, Hassan-King, M, Nunes, C, Bennett, S, Whittle, H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC175062/
https://ncbi.nlm.nih.gov/pubmed/9038290
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