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Bacteriostatic and bactericidal activities of beta-lactams against Streptococcus (Enterococcus) faecium are associated with saturation of different penicillin-binding proteins.

The MICs and MBCs of benzylpenicillin, ampicillin, cefotaxime, and methicillin were evaluated against a Streptococcus (Enterococcus) faecium wild-type strain and against three mutants hyperproducing PBP 5 in cells incubated at both optimal and suboptimal temperatures. In the wild-type strain grown a...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Lleó, M M, Canepari, P, Cornaglia, G, Fontana, R, Satta, G
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3435109/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.10.1618
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