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Role of extracellular iron in the action of the quinone antibiotic streptonigrin: mechanisms of killing and resistance of Neisseria gonorrhoeae.

The quinone antibiotic streptonigrin is believed to kill bacteria by promoting formation of oxygen radicals. This antibiotic has also been used to select resistant bacterial mutants, some of which vary in iron utilization. We examined the effects of streptonigrin on Neisseria gonorrhoeae and several...

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Bibliographic Details
Main Authors: Cohen, M S, Chai, Y, Britigan, B E, McKenna, W, Adams, J, Svendsen, T, Bean, K, Hassett, D J, Sparling, P F
Format: Artigo
Language:Inglês
Published: 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC174980/
https://ncbi.nlm.nih.gov/pubmed/2829710
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