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Role of extracellular iron in the action of the quinone antibiotic streptonigrin: mechanisms of killing and resistance of Neisseria gonorrhoeae.

The quinone antibiotic streptonigrin is believed to kill bacteria by promoting formation of oxygen radicals. This antibiotic has also been used to select resistant bacterial mutants, some of which vary in iron utilization. We examined the effects of streptonigrin on Neisseria gonorrhoeae and several...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Cohen, M S, Chai, Y, Britigan, B E, McKenna, W, Adams, J, Svendsen, T, Bean, K, Hassett, D J, Sparling, P F
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1987
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.10.1507
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