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Decreasing TNFα results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis

Granulomatous experimental autoimmune thyroiditis (G-EAT) is induced in DBA/1 mice by adoptive transfer of mouse thyroglobulin (MTg)-primed spleen cells. TNFα is an important proinflammatory cytokine and apoptotic molecule involved in many autoimmune diseases. To study its role in G-EAT, anti-TNFα m...

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Detalhes bibliográficos
Main Authors: Chen, Kemin, Wei, Yongzhong, Sharp, Gordon C., Braley-Mullen, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748426/
https://ncbi.nlm.nih.gov/pubmed/17046971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0606402
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