Penetration of ceftazidime into heart valves and subcutaneous and muscle tissue of patients undergoing open-heart surgery.

Patients undergoing open-heart surgery were given an intravenous bolus injection of 2 g of ceftazidime as a single dose over a period of 5 min. Within 12 h, ceftazidime concentrations in serum declined from 55.8 to 3.9 mg/liter. Subcutaneous tissue concentrations of the drug decreased from 21.0 to 2...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Frank, U, Kappstein, I, Schmidt-Eisenlohr, E, Schlosser, V, Spillner, G, Schindler, M, Daschner, F D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3300542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.5.813
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