Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth.

Several of the new 4-quinolones significantly increase the incorporation of [3H]thymidine into the DNA of mitogen-stimulated human lymphocytes. This study suggests that ciprofloxacin inhibits de novo pyrimidine biosynthesis, thereby resulting in a compensatory increase in the uptake of pyrimidine pr...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Forsgren, A, Bredberg, A, Pardee, A B, Schlossman, S F, Tedder, T F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3606077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.5.774
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