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Evolutionary theory for modifiers of epistasis using a general symmetric model
Genetic interactions in fitness are studied by using modifier theory. The effects on fitness of two linked genes are perturbed by alleles at a third linked locus that controls the extent of epistasis in fitness between the first two. This epistasis is determined by a symmetric interaction matrix, an...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1748238/ https://ncbi.nlm.nih.gov/pubmed/17167052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608569103 |
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