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Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins

High-throughput screening and optimization experiments are critical to a number of fields, including chemistry and structural and molecular biology. The separation of these two steps may introduce false negatives and a time delay between initial screening and subsequent optimization. Although a hybr...

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Bibliografiske detaljer
Main Authors: Li, Liang, Mustafi, Debarshi, Fu, Qiang, Tereshko, Valentina, Chen, Delai L., Tice, Joshua D., Ismagilov, Rustem F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748211/
https://ncbi.nlm.nih.gov/pubmed/17159147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607502103
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