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Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms

African sleeping sickness is a disease caused by Trypanosoma brucei. T. brucei proliferate rapidly in the mammalian bloodstream as long, slender forms, but at higher population densities they transform into nondividing, short, stumpy forms. This is thought to be a mechanism adopted by T. brucei to e...

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Detalhes bibliográficos
Main Authors: Laxman, Sunil, Riechers, Aaron, Sadilek, Martin, Schwede, Frank, Beavo, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748198/
https://ncbi.nlm.nih.gov/pubmed/17142316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608971103
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