Imipenem resistance in Pseudomonas aeruginosa resulting from diminished expression of an outer membrane protein.

The mechanism of Pseudomonas aeruginosa resistance to imipenem in five imipenem-susceptible clinical isolates and in their resistant counterparts was investigated. The frequency for selecting imipenem-resistant variants ranged from 2.7 X 10(-5) to 2.1 X 10(-8) and was comparable to those for other b...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Büscher, K H, Cullmann, W, Dick, W, Opferkuch, W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3111361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.5.703
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