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Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns

We describe a method based on the principle of entropy maximization to identify the gene interaction network with the highest probability of giving rise to experimentally observed transcript profiles. In its simplest form, the method yields the pairwise gene interaction network, but it can also be e...

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Detalhes bibliográficos
Main Authors: Lezon, Timothy R., Banavar, Jayanth R., Cieplak, Marek, Maritan, Amos, Fedoroff, Nina V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748172/
https://ncbi.nlm.nih.gov/pubmed/17138668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609152103
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