Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a randomised controlled trial

Background: Guidelines recommend inhaled corticosteroids (ICS) as maintenance treatment for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator forced expiratory volume in 1 second (FEV(1)) <50% predicted and frequent exacerbations, although they have only a smal...

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Detalhes bibliográficos
Main Authors: Wouters, E, Postma, D, Fokkens, B, Hop, W, Prins, J, Kuipers, A, Pasma, H, Hensing, C, Creutzberg, E, t for
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2005
Assuntos:
Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1747438/
https://ncbi.nlm.nih.gov/pubmed/15923248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2004.034280
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