Molecular genetic analysis of cephalosporinase production and its role in beta-lactam resistance in clinical isolates of Enterobacter cloacae.

Two strains of Enterobacter cloacae were isolated from a patient before (strain MHN1) and during (strain MHN2) treatment with moxalactam and gentamicin. Strain MHN1 exhibited inducible ampC cephalosporinase production. In contrast, strain MHN2 expressed the enzyme constitutively at a 3,000-fold high...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Nicolas, M H, Honore, N, Jarlier, V, Philippon, A, Cole, S T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3032094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.2.295
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