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Attenuation of bleomycin induced pulmonary fibrosis in mice using the heme oxygenase inhibitor Zn-deuteroporphyrin IX-2,4-bisethylene glycol

Methods: Zndtp (10 µmol/kg) was administered subcutaneously twice daily to mice 1 week following the intratracheal instillation of 0.025 U bleomycin. Animals were killed 10 or 21 days after bleomycin instillation and indices of lung damage and fibrosis were evaluated. Results: Bleomycin treatment in...

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Bibliografski detalji
Glavni autori: Atzori, L, Chua, F, Dunsmore, S, Willis, D, Barbarisi, M, McAnulty, R, Laurent, G
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746982/
https://ncbi.nlm.nih.gov/pubmed/14985557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2003.008979
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