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In vivo evaluation of tigemonam, a novel oral monobactam.

Tigemonam, a new monobactam with excellent activity against gram-negative bacteria, was evaluated for in vivo efficacy and absorption after oral administration to laboratory animals. Tigemonam is absorbed when administered orally to mice and dogs. In a variety of gram-negative systemic infections in...

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Published in:Antimicrob Agents Chemother
Main Authors: Clark, J M, Olsen, S J, Weinberg, D S, Dalvi, M, Whitney, R R, Bonner, D P, Sykes, R B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3551830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.2.226
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