Effect of cilomilast (Ariflo) on TNF-α, IL-8, and GM-CSF release by airway cells of patients with COPD

Background: Inflammation in chronic obstructive pulmonary disease (COPD) is characterised by increased neutrophilic infiltration of the airways. Cilomilast, a novel selective phosphodiesterase 4 inhibitor in clinical development for COPD treatment, exerts anti-inflammatory effects. The ability of ci...

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Detalhes bibliográficos
Main Authors: Profita, M, Chiappara, G, Mirabella, F, Di, G, Chimenti, L, Costanzo, G, Riccobono, L, Bellia, V, Bousquet, J, Vignola, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
Assuntos:
Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746747/
https://ncbi.nlm.nih.gov/pubmed/12832668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.7.573
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