Relationship of anti-GM-CSF antibody concentration, surfactant protein A and B levels, and serum LDH to pulmonary parameters and response to GM-CSF therapy in patients with idiopathic alveolar proteinosis

Methods: Blood levels of anti-GM-CSF antibodies, SP-A, SP-B, LDH, and [A – a]DO(2), VC, and TLCO were measured before rhGM-CSF treatment and every 2 weeks thereafter in 14 patients with AP. Results: At baseline, high levels of anti-GM-CSF antibodies and increased SP-A and SP-B levels were seen in al...

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Main Authors: Seymour, J, Doyle, I, Nakata, K, Presneill, J, Schoch, O, Hamano, E, Uchida, K, Fisher, R, Dunn, A
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2003
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746613/
https://ncbi.nlm.nih.gov/pubmed/12612307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.3.252
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