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Effect of tiotropium bromide on circadian variation in airflow limitation in chronic obstructive pulmonary disease

Background: In chronic obstructive pulmonary disease (COPD), the degree of circadian variation in forced expiratory volume in 1 second (FEV(1)) and the influence of anticholinergic blockade is not known. Tiotropium is a long acting inhaled anticholinergic bronchodilator that increases daytime FEV(1)...

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Detalhes bibliográficos
Main Authors: Calverley, P, Lee, A, Towse, L, van Noord, J, Witek, T, Kelsen, S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746483/
https://ncbi.nlm.nih.gov/pubmed/14514937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.10.855
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