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Contrasting effects of allergen challenge on airway responsiveness to cysteinyl leukotriene D(4) and methacholine in mild asthma

Background: Cysteinyl leukotrienes (cysteinyl-LTs) have been implicated in the pathogenesis of allergen induced airway responses. Airway responsiveness (AR) to inhaled cysteinyl-LTs is dramatically increased following allergen challenge in animal studies. The effect in man has not been evaluated. Me...

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Main Authors: Ketchell, R, D'Amato, M, Jensen, M, O'Connor, B
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746387/
https://ncbi.nlm.nih.gov/pubmed/12096198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.57.7.575
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