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Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice.

A possible role for tumor necrosis factor (TNF) alpha during Trypanosoma cruzi infection was explored by using transgenic mice expressing in blood high levels of a soluble TNFR1-FcIgG3 fusion protein, which neutralizes the effects of TNF in vivo. Nontransgenic littermates were used as controls. The...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Lima, E C, Garcia, I, Vicentelli, M H, Vassalli, P, Minoprio, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9009297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.2.457-465.1997
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