Localisation of transforming growth factor β(1) and β(3) mRNA transcripts in normal and fibrotic human lung

BACKGROUND—Transforming growth factor β(1) is implicated in the pathogenesis of lung fibrosis. It promotes extracellular matrix accumulation by increasing procollagen synthesis and reducing degradation. TGFβ(1) gene and protein expression increase in experimental lung fibrosis, and TGFβ(1) antibodie...

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Hauptverfasser: Coker, R, Laurent, G, Jeffery, P, du Bois, R M, Black, C, McAnulty, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2001
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746092/
https://ncbi.nlm.nih.gov/pubmed/11413354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.7.549
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