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Regulation of the effects of TGF-β1 by activation of latent TGF-β1 and differential expression of TGF-β receptors (TβR-I and TβR-II) in idiopathic pulmonary fibrosis

BACKGROUND—Idiopathic pulmonary fibrosis (IPF) is characterised by subpleural fibrosis that progresses to involve all areas of the lung. The expression of transforming growth factor-β1 (TGF-β1), a potent regulator of connective tissue synthesis, is increased in lung sections of patients with IPF. TG...

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Detalhes bibliográficos
Main Authors: Khalil, N, Parekh, T, O'Connor, R, Antman, N, Kepron, W, Yehaulaeshet, T, Xu, Y, Gold, L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745982/
https://ncbi.nlm.nih.gov/pubmed/11713352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.12.907
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