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Association of α(1)-antichymotrypsin deficiency with milder lung disease in patients with cystic fibrosis

BACKGROUND—Cystic fibrosis (CF) is characterised by an excess of free proteinases that destroy lung tissue. Despite this, previous studies have shown that patients with CF with a mild deficiency variant of the proteinase inhibitor α(1)-antitrypsin have less, rather than more, severe pulmonary diseas...

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Detalhes bibliográficos
Main Authors: Mahadeva, R, Sharples, L, Ross-Russell, R, Webb, A, Bilton, D, Lomas, D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745909/
https://ncbi.nlm.nih.gov/pubmed/11120905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.1.53
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