Expression of an antisense hla fragment in Staphylococcus aureus reduces alpha-toxin production in vitro and attenuates lethal activity in a murine model.

Isogeneic bacterial strains that differ only in the production of a single microbial factor have been invaluable in studying the pathogenesis of bacterial infections. The targeted, intentional inactivation of a gene encoding a potential virulence determinant generally requires homologous recombinati...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kernodle, D S, Voladri, R K, Menzies, B E, Hager, C C, Edwards, K M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC174573/
https://ncbi.nlm.nih.gov/pubmed/8975909
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk