Exhaled 8-isoprostane as a new non-invasive biomarker of oxidative stress in cystic fibrosis

BACKGROUND—Cystic fibrosis is characterised by oxidative stress in the airways. Isoprostanes are prostaglandin isomers formed by free radical catalysed peroxidation of arachidonic acid. 8-Isoprostane is increased in interstitial lung diseases, asthma, chronic obstructive pulmonary disease, and adult...

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Bibliographic Details
Main Authors: Montuschi, P., Kharitonov, S., Ciabattoni, G., Corradi, M., van Rensen, L., Geddes, D., Hodson, M., Barnes, P.
Format: Artigo
Language:Inglês
Published: BMJ Group 2000
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745696/
https://ncbi.nlm.nih.gov/pubmed/10679539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.55.3.205
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