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An iron- and fur-repressed Legionella pneumophila gene that promotes intracellular infection and encodes a protein with similarity to the Escherichia coli aerobactin synthetases.

Legionella pneumophila, a parasite of alveolar macrophages, requires iron for intra- and extracellular growth. Although its mechanisms for iron assimilation are poorly understood, this bacterium produces Fur, a protein that can repress gene transcription in response to iron concentration. Because ir...

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Bibliografiska uppgifter
I publikationen:Infect Immun
Huvudupphov: Hickey, E K, Cianciotto, N P
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8975903/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.1.133-143.1997
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