Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/permeability-increasing factor.

Well-defined polysaccharides, such as beta1-4-linked D-mannuronic acid (poly[M]) derived from Pseudomonas aeruginosa, induce monocytes to produce tumor necrosis factor (TNF) through a pathway involving membrane CD14. In this study we have investigated the effects of soluble CD14 (sCD14), lipopolysac...

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Pubblicato in:	Infect Immun
Autori principali:	Jahr, T G, Ryan, L, Sundan, A, Lichenstein, H S, Skjåk-Braek, G, Espevik, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8975896/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.1.89-94.1997
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