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Extended tumour necrosis factor/HLA-DR haplotypes and asthma in an Australian population sample

BACKGROUND—Tumour necrosis factor (TNF) is a potent pro-inflammatory cytokine which is prominent in asthmatic airways. TNF shows genetic variations in secretion which are linked to polymorphisms in the TNF gene complex and the surrounding major histocompatibility (MHC) locus. These polymorphisms do...

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Main Authors: Moffatt, M., James, A., Ryan, G., Musk, A, Cookson, W.
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745569/
https://ncbi.nlm.nih.gov/pubmed/10456966
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