Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5'-monophosphate in asthma

BACKGROUND—Nitric oxide (NO) may be bronchoprotective in asthma, possibly due to a direct action on airway smooth muscle or through mast cell stabilisation. To investigate this the effects of two doses of nebulised N(G)-nitro-L-arginine methyl ester (L-NAME), a non-selective NO synthase (NOS) inhibi...

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Main Authors: Taylor, D, McGrath, J, Orr, L, Barnes, P, O'Connor, B
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 1998
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745235/
https://ncbi.nlm.nih.gov/pubmed/9713448
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